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As a research compound, AOD9604 UK carries a well-characterised pre-clinical and early-phase clinical research profile developed primarily through the work of Metabolic Pharmaceuticals, with published studies spanning lipid metabolism, adipose biology, 3-adrenergic receptor regulation, cartilage biology, and safety pharmacology

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Furthermore, the PPAR- agonist, WY14643, seems to reduce the renal dysfunction and injury associated with I/R (Sivarajah et al., 2002), while benzafibrate inhibits cisplatin-mediated injury by preventing the proximal tubule cell death (Nagothu et al., 2005)